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About
Professor Lyndell Lim
Head of uveitis and retinal vascular disease research, Chief Medical Officer, Cerulea Clinical Trials
Professor Lyndell Lim is a uveitis and medical retina subspecialist, leads CERA’s research in the fields of ocular inflammatory disease and diabetic retinopathy and is Chief Medical Officer of Cerulea Clinical Trials.
Professor Lyndell Lim
Head of uveitis and retinal vascular disease research, Chief Medical Officer, Cerulea Clinical Trials
MBBS, DMedSci, FRANZCO
Professor Lyndell Lim is uveitis and medical retina subspecialist, leads CERA’s uveitis and retinal vascular disease research and is Chief Medical Officer of Cerulea Clinical Trials.
After completing her ophthalmology training in Melbourne, Prof Lim then completed two Fellowships – one in medical retina at the Royal Victorian Eye and Ear Hospital, and one in uveitis/ocular inflammatory disease at the Casey Eye Institute, Portland, Oregon, USA.
Prof Lim’s main research interests are clinical studies in the field of uveitis and ocular immunology, and diabetic retinopathy. Her team runs both investigator-initiated and sponsored clinical trials that aim to investigate new treatments in a variety of ophthalmic diseases.
Key research questions
- Can we find new treatments for non-infectious uveitis that are better tolerated (i.e. fewer side effects) and are more effective than what is currently available?
- How can we gain a better understanding of the causes and risk factors for the development and progression of uveitis?
- Are there any biomarkers that we can find that will help predict who may get recurrent, or more severe uveitis?
- How can we better treat diabetic retinopathy and diabetic macular oedema?
- How can we better manage diabetic eye disease when there is higher risk of progression, such as during pregnancy or cataract surgery?
- Is it possible to predict visual outcomes following treatment for diabetic eye diseases?
Current projects
Selected publications
My team
Key collaborators
Funding and support
Current projects
- Prof Lim’s team are involved with ongoing clinical trials of new treatments for uveitis through Cerulea Clinical Trials.
- We have a number of research collaborations and ongoing projects that all aim to answer our key research questions.
Selected publications
Rathinam SR, Gonzales JA, Thundikandy R, Kanakath A, Murugan SB, Vedhanayaki R, Lim LL, Suhler EB, Al-Dhibi HA, Doan T, Keenan JD, Rao MM, Ebert CD, Nguyen HH, Kim E, Porco TC, Acharya NR; FAST Research Group. Effect of Corticosteroid-Sparing Treatment With Mycophenolate Mofetil vs Methotrexate on Inflammation in Patients With Uveitis A Randomized Clinical Trial. JAMA 2019 Sept 10; 322(10):936-945 DOI: 10.1001/jama.2019.12618
Chiu ZK, Lim LL, Rogers SL, Hall AJ. Patterns of Vitamin D Levels and Exposures in Active and Inactive Non-Infectious Uveitis Patients. Ophthalmology 2019 Jul 11 [Epub ahead of print] DOI: 10.1016/j.ophtha.2019.06.030
Lim LL, Silva DG, Lo TC, Pimentel RS, Butzkueven H, Hall AJ. Uveitis in Patients with Multiple Sclerosis in Clinical Trials of Fingolimod: Incidence, Prevalence and Impact on Disease Course. Ophthalmology 2019 Mar; 126(3):438-444 DOI: 10.1016/j.ophtha.2018.10.013
Kandasamy R, Constantinou M, Rogers SL, Sandhu SS, Wickremasinghe S, Al-Qureshi S, Lim LL. Prospective randomised clinical trial of intravitreal bevacizumab versus triamcinolone in eyes with diabetic macular oedema undergoing cataract surgery: 6-month results. Br J Ophthalmology 2019 Feb 28
Ma SP, Rogers SL, Hall AJ, Hodgson LAB, Brennan J, Stawell RJ, Lim LL. Sarcoidosis-related Uveitis: Clinical Presentation, Disease Course, and Rates of Systemic Disease Progression After Uveitis Diagnosis. Am J Opththal. 2019 Feb 189:30-6 DOI: 10.1016/j.ajo.2018.09.013
See more publications
My team
- Associate Professor Elaine Chong – Senior Research Fellow
- Dr Thanh Nguyen – Senior Research Fellow
- Dr Sukhpal Singh Sandhu – Senior Research Fellow
- Associate Professor Sanjeewa Wickremasinghe – Senior Research Fellow
- Kelly Mikunda – Executive Assistant
- Sophie Rogers – Biostatistician
Key collaborators
- MUST Group (Doug Jabs, USA)
- FAST Group (Nisha Acharaya, USA)
- Peter McCluskey (Sydney)
- Mark Gillies (Sydney)
- Samantha Fraser-Bell (Sydney)
- Rachael Neiderer (Auckland)
- Jennifer Wilkinson-Berka (UoM)
Funding and support
Thank you to the following organisations for their support:
- NHMRC
- ORIA
- JDRF
- NIH
- Ramaciotti
- Diabetes Australia
- Alfred Fenton Trust
Contact Professor Lyndell Lim
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