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Improving prediction of disease progression in early stages of AMD

To pave the way for therapeutic innovation, this project aims to identify better imaging biomarkers for the early stages of age-related macular degeneration (AMD) that can identify high-risk individuals to target for preventative treatments.

Supervisors: Associate Professor Zhichao Wu and Professor Robyn Guymer AM
Email: wu.z@unimelb.edu.au; rh.guymer@unimelb.edu.au
Suitable for: PhD

 

A major impediment to the discovery of preventative interventions in the early stages of age-related macular degeneration (AMD) is the need for large and lengthy clinical trials to assess their efficacy. This is due to our current inability to identify those at high risk of progression to target for such trials, and those for whom such preventative treatments are eventually most beneficial for.

This project thus seeks to identify and establish novel imaging biomarkers that predict late AMD development, needed to pave the way for therapeutic innovation. These imaging biomarkers are also needed to enhance clinical risk stratification for the one in seven Australians over 50 years old with the early stages of AMD at risk of irreversible vision loss.

To learn more or apply for this opportunity, please email Associate Professor Zhichao Wu at wu.z@unimelb.edu.au
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