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Student opportunities
Neovascular AMD: Imaging biomarkers of poor functional outcomes
Although treatments are available for the acute complications of neovascular age-related macular degeneration (AMD), many patients develop longer-term complications that result in poor vision outcomes. This project aims to identify better imaging biomarkers of significant vision loss, which are needed to facilitate trials of new treatments to prevent poor long-term functional outcomes.
Supervisors: Associate Professor Zhichao Wu and Professor Robyn Guymer AM
Email: wu.z@unimelb.edu.au; rh.guymer@unimelb.edu.au
Suitable for: PhD
The treatment of neovascular age-related macular degeneration (AMD) was first revolutionised nearly 20 years ago, and as with treatments currently used today, improves vision significantly in the short term by suppressing the acute complications. However, many patients continue to develop longer-term complications that result in poor vision outcomes despite such treatments.
This project thus seeks to identify better imaging biomarkers of such long-term complications at an earlier time point. It will harness the power of a novel functional testing approach developed by our group to accurately identify local regions of deeply impaired visual sensitivity, so that anatomical changes the account for such changes can be accurately identified. These imaging biomarkers will then serve to facilitate trials of new treatments to prevent such poor long-term outcomes from neovascular AMD.